ORKAMBI

NDC 51167-700 · Vertex Pharmaceuticals Incorporated

Generic namelumacaftor and ivacaftor

Dosage formTABLET, FILM COATED

RouteORAL

Active ingredient(s)LUMACAFTOR, IVACAFTOR

Strength125; 100 mg/1; mg/1

Pharmacologic classChloride Channel Activation Potentiators [MoA], Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC], Cytochrome P450 2B6 Inducers [MoA], Cytochrome P450 2C19 Inducers [MoA], Cytochrome P450 2C8 Inducers [MoA], Cytochrome P450 2C8 Inhibitors [MoA], Cytochrome P450 2C9 Inducers [MoA], Cytochrome P450 2C9 Inhibitors [MoA], Cytochrome P450 2C9 Inhibitors [MoA], Cytochrome P450 3A Inducers [MoA], Cytochrome P450 3A Inhibitors [MoA], P-Glycoprotein Inducers [MoA], P-Glycoprotein Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]

Marketing categoryNDA

Packages

51167-700-02 — 4 CARTON in 1 BOX (51167-700-02) / 7 BLISTER PACK in 1 CARTON / 4 TABLET, FILM COATED in 1 BLISTER PACK

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

51167-122 — lumacaftor and ivacaftor, 51167-200 — ivacaftor, 51167-300 — ivacaftor, 51167-400 — ivacaftor, 51167-500 — lumacaftor and ivacaftor, 51167-600 — ivacaftor, 51167-770 — ivacaftor, 51167-785 — ivacaftor, 51167-809 — lumacaftor and ivacaftor, 51167-900 — lumacaftor and ivacaftor

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels