NIGHTTIME SEVERE COLD AND FLU

NDC 51316-477 · CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED

Generic nameAcetaminophen, dextromethorphan HBr, doxylamine succinate, phenylephrine HCl

Dosage formSOLUTION

RouteORAL

Active ingredient(s)ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDE

Strength650; 20; 12.5; 10 mg/30mL; mg/30mL; mg/30mL; mg/30mL

Pharmacologic classAdrenergic alpha1-Agonists [MoA], Antihistamine [EPC], Histamine Receptor Antagonists [MoA], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]

Marketing categoryOTC MONOGRAPH DRUG

Packages

51316-477-40 — 355 mL in 1 BOTTLE (51316-477-40)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

51316-415 — Acetaminophen, Dextromethorphan HBr, Doxylamine Succinate, Phenylephrine HCl, 51316-421 — Acetaminophen, Dextromethorphan HBr, 51316-429 — dextromethorphan polistirex, 51316-430 — Dextromethorphan HBr, Doxylamine Succinate, 51316-431 — Dextromethorphan HBr, Doxylamine Succinate, 51316-444 — Acetaminophen, 51316-449 — Acetaminophen, 51316-450 — Acetaminophen, 51316-466 — Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, 51316-473 — dextromethorphan hydrobromide, guaifenesin, 51316-485 — Diphenhydramine HCl, Phenylephrine HCl, 51316-499 — Dextromethorphan HBr, Doxylamine Succinate, 51316-500 — Dextromethorphan HBr, Guaifenesin, 51316-504 — acetaminophen, 51316-513 — brompheniramine maleate, dextromethorphan hydrobromide, 51316-516 — Acetaminophen, Guaifenesin, Phenylephrine HCl, 51316-525 — Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 51316-526 — ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCL, 51316-530 — Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 51316-533 — acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride, +4930 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels