NIGHTTIME COLD AND FLU

NDC 51316-884 · CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED

Generic nameAcetaminophen, Dextromethorphan Hydrobromide, Doxylamine succinate

Dosage formSOLUTION

RouteORAL

Active ingredient(s)ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE

Strength650; 30; 12.5 mg/30mL; mg/30mL; mg/30mL

Pharmacologic classAntihistamine [EPC], Histamine Receptor Antagonists [MoA], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA]

Marketing categoryOTC MONOGRAPH DRUG

Packages

51316-884-40 — 355 mL in 1 BOTTLE (51316-884-40)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

51316-791 — Dextromethorphan Hydrobromide, Doxylamine Succinate, 51316-803 — Acetaminophen, Dextromethorphan HBr, 51316-808 — Dextromethorphan HBr, Guaifenesin, 51316-809 — Acetaminophen, Guaifenesin, 51316-815 — Dextromethorphan HBr, guaifenesin, Phenylephrine HCl, 51316-826 — Dextromethorphan Hydrobromide, Guaifenesin, 51316-830 — Dextromethorphan hydrobromide, Guaifenesin, 51316-858 — dextromethorphan hydrobromide, guaifenesin, 51316-863 — Acetaminophen, Diphenhydramine HCL, 51316-877 — Dextromethorphan hydrobromide, 51316-896 — Acetaminophen Dextromethorphan HBr Phenylephrine HCl, 51316-897 — Acetaminophen, Dextromethorphan HBr, 51316-921 — Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine succinate, 51316-927 — Acetaminophen, Guaifenesin, Phenylephrine HCl, 51316-940 — Acetaminophen, Guaifenesin, 51316-943 — dextromethorphan polistirex, 51316-945 — Acetaminophen, Chlorpheniramine Maleate and Dextromethophan HBr, 51316-955 — Acetaminophen and Ibuprofen, 51316-963 — Acetaminophen, Dextromethorphan HBr, Triprolidine HCl, 51316-969 — Acetaminophen 650mg, +4482 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels