Tylenol Sinus Severe

NDC 53209-1004 · Morning Star OTC

Generic nameAcetaminophen, Guaifenesin, and Phenylephrine Hydrochloride

Dosage formTABLET, COATED

RouteORAL

Active ingredient(s)ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE

Strength325; 200; 5 mg/1; mg/1; mg/1

Pharmacologic classAdrenergic alpha1-Agonists [MoA], Decreased Respiratory Secretion Viscosity [PE], Expectorant [EPC], Increased Respiratory Secretions [PE], alpha-1 Adrenergic Agonist [EPC]

Marketing categoryOTC MONOGRAPH DRUG

Packages

53209-1004-2 — 25 BLISTER PACK in 1 POUCH (53209-1004-2) / 2 TABLET, COATED in 1 BLISTER PACK (53209-1004-1)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

53145-696 — Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin and Phenylephrine Hydrochloride, 53145-697 — DEXTROMETHORPHAN HBr, GUAIFENESIN, PHENYLEPHRINE HCL, 53145-830 — Acetaminophen, 53163-101 — BROMPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, 53163-104 — Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 53163-113 — Dextromethorphan HBr, Guaifenesin, 53185-005 — ACETAMINOPHEN, 53209-1001 — Acetaminophen, 53209-1002 — acetaminophen and diphenhydramine hydrochloride, 53209-1003 — Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride, 53329-194 — acetaminophen, 53329-195 — acetaminophen, 53329-196 — acetaminophen, 53329-604 — Acetaminophen, 53329-643 — Acetaminophen, 53345-004 — acetaminophen, dextromethorphan hydrobromide, phenylephrine hydrochloride, 53345-006 — acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, 53345-010 — ACETAMINOPHEN, 53345-012 — acetaminophen, phenylephrine hydrochloride, 53345-013 — Acetaminophen, Doxylamine succinate, Phenylephrine hydrochloride, +4982 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels