Guaifenesin and Dextromethorphan Hydrobromide

NDC 58657-504 · Method Pharmaceuticals

Generic nameGuaifenesin and Dextromethorphan Hydrobromide

Dosage formSYRUP

RouteORAL

Active ingredient(s)DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN

Strength10; 100 mg/5mL; mg/5mL

Pharmacologic classDecreased Respiratory Secretion Viscosity [PE], Expectorant [EPC], Increased Respiratory Secretions [PE], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA]

Marketing categoryOTC MONOGRAPH DRUG

Packages

58657-504-08 — 237 mL in 1 BOTTLE, PLASTIC (58657-504-08)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

58602-825 — Guaifenesin and Dextromethorphan HBr, 58602-833 — Guaifenesin and Pseudoephedrine HCl, 58602-834 — Guaifenesin and Pseudoephedrine HCl, 58602-849 — Guaifenesin and Dextromethorphan HBr, 58602-853 — Guaifenesin, 58602-857 — Guaifenesin, 58602-864 — Guaifenesin, 58602-865 — Guaifenesin, 58602-871 — Guaifenesin and Dextromethorphan HBr, 58657-500 — Codeine Phosphate and Guaifenesin, 58657-505 — Guaifenesin and Dextromethorphan Hydrobromide, 58657-508 — Guaifenesin, 58657-509 — Guaifenesin, 58809-187 — Dextromethorphan HBr, Guaifenesin, 58809-217 — Choline Salicylate, Dextromethorphan Hydrobromide, Guaifenesin, 58809-218 — Choline Salicylate,Guaifenesin, 58809-555 — DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE, 58933-550 — Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, 58933-552 — Acetaminophen, Dextromethorphan HBr, 59148-053 — dextromethorphan hydrobromide and quinidine sulfate, +2508 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels