Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz

NDC 70264-016 · R J General Corporation

Generic namechlorpheniramine maleate, acetaminophen, phenylephrine hydrochloride, dextromethorphan hydrobromide

Dosage formTABLET, EFFERVESCENT

RouteORAL

Active ingredient(s)PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, CHLORPHENIRAMINE MALEATE

Strength250; 2; 10; 5 mg/1; mg/1; mg/1; mg/1

Pharmacologic classAdrenergic alpha1-Agonists [MoA], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]

Marketing categoryOTC MONOGRAPH DRUG

Packages

70264-016-01 — 30 POUCH in 1 CARTON (70264-016-01) / 2 TABLET, EFFERVESCENT in 1 POUCH

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

70069-801 — PHENYLEPHRINE HYDROCHLORIDE, 70069-802 — PHENYLEPHRINE HYDROCHLORIDE, 70069-803 — PHENYLEPHRINE HYDROCHLORIDE, 70069-811 — PHENYLEPHRINE HYDROCHLORIDE, 70069-812 — PHENYLEPHRINE HYDROCHLORIDE, 70069-813 — PHENYLEPHRINE HYDROCHLORIDE, 70121-1577 — Phenylephrine hydrochloride, 70121-1578 — Phenylephrine hydrochloride, 70121-1579 — Phenylephrine hydrochloride, 70264-012 — acetaminophen, caffeine, and pyrilamine maleate, 70264-025 — ACETAMINPHEN, 70264-026 — ACETAMINOPHEN, 70264-027 — ACETAMINOPHEN, 70264-028 — ACETAMINOPHEN, 70264-040 — Acetaminophen 250 mg and Ibuprofen 125 mg, 70264-045 — Acetaminophen, Aspirin (NSAID), Caffeine, 70264-047 — ACETAMINOPHEN, DEXTROMETHORPHAN HBr, 70512-865 — Phenylephrine Hydrochloride, 70512-866 — Phenylephrine Hydrochloride, 70518-1134 — Butalbital, Acetaminophen, and Caffeine, +4944 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels