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Diphenhydramine Hydrochloride

NDC 72789-317 · PD-Rx Pharmaceuticals, Inc.

Generic nameDiphenhydramine Hydrochloride
Dosage formCAPSULE
RouteORAL
Active ingredient(s)DIPHENHYDRAMINE HYDROCHLORIDE
Strength25 mg/1
Pharmacologic classHistamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

72789-317-10 — 10 CAPSULE in 1 BOTTLE, PLASTIC (72789-317-10)

72789-317-12 — 12 CAPSULE in 1 BOTTLE, PLASTIC (72789-317-12)

72789-317-15 — 15 CAPSULE in 1 BOTTLE, PLASTIC (72789-317-15)

72789-317-20 — 20 CAPSULE in 1 BOTTLE, PLASTIC (72789-317-20)

72789-317-30 — 30 CAPSULE in 1 BOTTLE, PLASTIC (72789-317-30)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

72288-379 — Diphenhydramine HCl, 72288-437 — Acetaminophen, Diphenhydramine HCl, 72288-479 — Diphenhydramine Hydrochloride, 72288-765 — Diphenhydramine HCl, 72288-964 — Acetaminophen, Diphenhydramine hydrochloride, Phenylephrine hydrochloride, 72476-113 — DIPHENHYDRAMINE HYDROCHLORIDE, 72476-171 — Acetaminophen and Diphenhydramine Hydrochloride, 72476-860 — Diphenhydramine HCl, 72476-916 — Diphenhydramine HCl, 72485-101 — Diphenhydramine Hydrochloride, 72789-532 — Diphenhydramine HCL, 72839-647 — Diphenhydramine HCl 2%, Zinc Acetate 0.1%, 73057-347 — Diphenhydramine HCl 50mg, 73057-348 — Diphenhydramine HCl 25mg, 73057-352 — Acetaminophen 500mg / Diphenhydramine HCl 25mg, 73097-004 — DIPHENHYDRAMINE HYDROCHLORIDE, 73097-013 — ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE, 73282-2518 — Diphenhydramine HCl, 73282-2520 — CalmCo Allergy Relief, 73282-2521 — Diphenhydramine HCl, +1029 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels