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Itch Relief

NDC 81522-751 · FSA Store Inc.

Generic nameDiphenhydramine HCl
Dosage formSPRAY
RouteTOPICAL
Active ingredient(s)DIPHENHYDRAMINE HYDROCHLORIDE
Strength20 mg/mL
Pharmacologic classHistamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
Marketing categoryOTC MONOGRAPH DRUG

Packages

81522-751-25 — 74 mL in 1 BOTTLE, SPRAY (81522-751-25)

Related Codes

Same active ingredient

FDA lists these products with the same active ingredient.

80136-785 — Diphenhydramine HCl, 80267-431 — Diphenhydramine Hydrochloride, 80489-005 — ZINC ACETATE , DIPHENHYDRAMINE, 80513-201 — Diphenhydramine HCl, 80513-301 — ACETAMINOPHEN, DEXTROMETHORPHAN HBR, PHENYLEPHRINE, 80513-383 — Diphenhydramine HCl, 80513-722 — Diphenhydramine HCl, 81522-095 — Acetaminophen and Diphenhydramine Hydrochloride, 81522-109 — DIPHENHYDRAMINE HYDROCHLORIDE, 81522-293 — Diphenhydramine Hydrochloride, 81522-916 — Diphenhydramine HCL, 82179-004 — Diphenhydramine HCL, 82442-530 — Diphenhydramine HCl, 82442-710 — Diphenhydramine hydrochloride, 82501-0186 — Diphenhydramine HCl, 82568-0004 — Diphenhydramine HCl, 82568-0005 — Diphenhydramine HCl, 82645-116 — Itch Relief Gel, 82645-901 — Itch Relief Gel, 82673-103 — Diphenhydramine HCl, Phenylephrine HCl, +1029 more

From the FDA National Drug Code Directory, retrieved August 24, 2026. Product listings are submitted by labelers; FDA does not verify them.

Read from: FDA National Drug Code Directory, product.txt and package.txt (accessdata.fda.gov/cder/ndctext.zip) — Snapshot retrieved 2026-08-24, loaded 2026-08-24; CMS Medicare Part B Drug Average Sales Price (ASP) Pricing Files (cms.gov/medicare/payment/part-b-drugs/asp-pricing-files) -- the NDC-HCPCS crosswalk and Part B payment limit files — 2026 Q3 (July 2026 release). All data sources · How to read the labels