C22.0 (Liver cell carcinoma) compared with D01.5 (Carcinoma in situ of liver, gallbladder and bile ducts), from the official CMS tabular data. C22.0 and D01.5 name the same anatomical site (hepatoma) with a different neoplasm behavior.
Same anatomical site, different neoplasm behavior.
Same site — carcinoma in situ (hepatoma)
The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.
Source: CMS Table of Neoplasms
Same site, different neoplasm behavior. C22.0 and D01.5 name the same anatomical site (hepatoma) with a different neoplasm behavior.
From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.
| C22.0Liver cell carcinoma | D01.5Carcinoma in situ of liver, gallbladder and bile ducts | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Liver cell carcinoma is a billable ICD-10-CM diagnosis code (C22.0). | Carcinoma in situ of liver, gallbladder and bile ducts is a billable ICD-10-CM diagnosis code (D01.5). |
| Includes | Hepatocellular carcinoma Hepatoma | Bowen's disease erythroplasia grade III intraepithelial neoplasia Queyrat's erythroplasia |
| Use additional code | code to identify: alcohol abuse and dependence (F10.-) hepatitis B (B16.-, B18.0-B18.1) | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources