C25.4 vs C75
C25.4 (Malignant neoplasm of endocrine pancreas) compared with C75 (Malignant neoplasm of other endocrine glands and related structures), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. C75 carries an Excludes1 note covering C25.4: “malignant neoplasm of endocrine pancreas (C25.4)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
No — do not report together. C75 carries an Excludes1 note covering C25.4: “malignant neoplasm of islets of Langerhans (C25.4)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| C25.4Malignant neoplasm of endocrine pancreas | C75Malignant neoplasm of other endocrine glands and related structures | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Malignant neoplasm of endocrine pancreas is a billable ICD-10-CM diagnosis code (C25.4). | Malignant neoplasm of other endocrine glands and related structures is a non-billable ICD-10-CM category code (C75). |
| Includes | Malignant neoplasm of islets of Langerhans | — |
| Use additional code | code to identify any functional activity. code to identify: alcohol abuse and dependence (F10.-) | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources