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C44.500 vs D49.2

C44.500 (Unspecified malignant neoplasm of anal skin) compared with D49.2 (Neoplasm of unspecified behavior of bone, soft tissue, and skin), from the official CMS tabular data. C44.500 and D49.2 name the same anatomical site (anus) with a different neoplasm behavior.

Relationship

Informational

Neoplasm table relationship

C44.500
Unspecified malignant neoplasm of anal skin
D49.2
Neoplasm of unspecified behavior of bone, soft tissue, and skin

Same anatomical site, different neoplasm behavior.

Same site — unspecified behavior (anus)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C44.500 and D49.2 name the same anatomical site (anus) with a different neoplasm behavior.

From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C44.500Unspecified malignant neoplasm of anal skinD49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionUnspecified malignant neoplasm of anal skin is a billable ICD-10-CM diagnosis code (C44.500).Neoplasm of unspecified behavior of bone, soft tissue, and skin is a billable ICD-10-CM diagnosis code (D49.2).
Includes
malignant neoplasm of sebaceous glands
malignant neoplasm of sweat glands
Unspecified malignant neoplasm of anal margin
Unspecified malignant neoplasm of perianal skin
'growth' NOS
neoplasm NOS
new growth NOS
tumor NOS

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources