C48.0 vs C49.3
C48.0 (Malignant neoplasm of retroperitoneum) compared with C49.3 (Malignant neoplasm of connective and soft tissue of thorax), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. C49.3 carries an Excludes2 note covering C48.0: “malignant neoplasm of retroperitoneum (C48.0)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| C48.0Malignant neoplasm of retroperitoneum | C49.3Malignant neoplasm of connective and soft tissue of thorax | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Malignant neoplasm of retroperitoneum is a billable ICD-10-CM diagnosis code (C48.0). | Malignant neoplasm of connective and soft tissue of thorax is a billable ICD-10-CM diagnosis code (C49.3). |
| Includes | — | malignant neoplasm of blood vessel malignant neoplasm of bursa malignant neoplasm of cartilage malignant neoplasm of fascia |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources