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C48.2 vs C49.3

C48.2 (Malignant neoplasm of peritoneum, unspecified) compared with C49.3 (Malignant neoplasm of connective and soft tissue of thorax), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C49.3 carries an Excludes2 note covering C48.2: “malignant neoplasm of peritoneum (C48.2)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C48.2Malignant neoplasm of peritoneum, unspecifiedC49.3Malignant neoplasm of connective and soft tissue of thorax
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of peritoneum, unspecified is a billable ICD-10-CM diagnosis code (C48.2).Malignant neoplasm of connective and soft tissue of thorax is a billable ICD-10-CM diagnosis code (C49.3).
Includes
malignant neoplasm of blood vessel
malignant neoplasm of bursa
malignant neoplasm of cartilage
malignant neoplasm of fascia

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources