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C49.3 vs C79.89

C49.3 (Malignant neoplasm of connective and soft tissue of thorax) compared with C79.89 (Secondary malignant neoplasm of other specified sites), from the official CMS tabular data. C49.3 and C79.89 name the same anatomical site (aorta) with a different neoplasm behavior.

Relationship

Informational

Neoplasm table relationship

C49.3
Malignant neoplasm of connective and soft tissue of thorax
C79.89
Secondary malignant neoplasm of other specified sites

Same anatomical site, different neoplasm behavior.

Same site — secondary malignancy (aorta)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C49.3 and C79.89 name the same anatomical site (aorta) with a different neoplasm behavior.

From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C49.3Malignant neoplasm of connective and soft tissue of thoraxC79.89Secondary malignant neoplasm of other specified sites
Billing statusBillableBillable
ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of connective and soft tissue of thorax is a billable ICD-10-CM diagnosis code (C49.3).Secondary malignant neoplasm of other specified sites is a billable ICD-10-CM diagnosis code (C79.89).
Includes
malignant neoplasm of blood vessel
malignant neoplasm of bursa
malignant neoplasm of cartilage
malignant neoplasm of fascia

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources