C78.89 (Secondary malignant neoplasm of other digestive organs) compared with C88.0 (Waldenström macroglobulinemia), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Distinct conditions — both may be reported.
“secondary neoplasm of spleen (C78.89)”
An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.
Source: CMS ICD-10-CM tabular instructional notes
Yes, when both are documented. C88.0 carries an Excludes2 note covering C78.89: “secondary neoplasm of spleen (C78.89)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
| C78.89Secondary malignant neoplasm of other digestive organs | C88.0Waldenström macroglobulinemia | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Secondary malignant neoplasm of other digestive organs is a billable ICD-10-CM diagnosis code (C78.89). | Waldenström macroglobulinemia is a non-billable ICD-10-CM category code (C88.0). |
| Includes | — | Lymphoplasmacytic lymphoma with IgM-production Macroglobulinemia (idiopathic) (primary) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources