Skip to main content

C88.0 ICD-10-CM Code: Waldenström macroglobulinemia

Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.

Official Registry Overview & Definition

Waldenström macroglobulinemia is a non-billable ICD-10-CM category code (C88.0). A more specific billable subcode must be selected for claims submission.

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for C88.0 in the official ICD-10-CM tabular list.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Lymphoplasmacytic lymphoma with IgM-production
  • Macroglobulinemia (idiopathic) (primary)

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Frequently Compared Codes

The official Excludes notes on C88.0 name these codes. Each comparison page covers when the two can — or must not — be reported together.

Change history

Verify Before Coding

  • Not billable as written — a more specific code is required: C88.00, C88.01.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Contextual Map

Every relationship of C88.0 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • C00-D49 — Chapter 2: Neoplasms (C00-D49) (C00-D49) [Hierarchy]
  • C81-C96 — Malignant neoplasms of lymphoid, hematopoietic and related tissue [Hierarchy]

Excludes1

  • C83.0 — Small cell B-cell lymphoma [Excludes1]: “small cell B-cell lymphoma (C83.0)” · check together

Clinical classification (CCSR)

  • NEO058 — Non-Hodgkin lymphoma [CCSR]

Nearest codes (18)

  • C88 — Malignant immunoproliferative diseases and certain other B-cell lymphomas [Sibling]
  • C88.00 — Waldenström macroglobulinemia not having achieved remission [Sibling]
  • C88.01 — Waldenström macroglobulinemia, in remission [Sibling]
  • C88.2 — Heavy chain disease [Sibling]
  • C88.20 — Heavy chain disease not having achieved remission [Sibling]
  • C88.21 — Heavy chain disease, in remission [Sibling]
  • C88.3 — Immunoproliferative small intestinal disease [Sibling]
  • C88.30 — Immunoproliferative small intestinal disease not having achieved remission [Sibling]
  • and 10 more

Change history

  • FY2025 — Became a non-billable header [Change history]

Relationships & Classification

Clinical classification (AHRQ CCSR):NEO058 — Non-Hodgkin lymphoma (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Frequently Asked Questions (FAQ) & Clinical Guidance

Can C88.0 be billed directly?

No. C88.0 (Waldenström macroglobulinemia) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to C88.0 in its code family, with their registry titles.

  • C88 — Malignant immunoproliferative diseases and certain other B-cell lymphomas
  • C88.00 — Waldenström macroglobulinemia not having achieved remission
  • C88.01 — Waldenström macroglobulinemia, in remission
  • C88.2 — Heavy chain disease
  • C88.20 — Heavy chain disease not having achieved remission
  • C88.21 — Heavy chain disease, in remission
  • C88.3 — Immunoproliferative small intestinal disease
  • C88.30 — Immunoproliferative small intestinal disease not having achieved remission
  • C88.31 — Immunoproliferative small intestinal disease, in remission
  • C88.4 — Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]

View all codes in the C88 family