D33.2 (Benign neoplasm of brain, unspecified) compared with D49.6 (Neoplasm of unspecified behavior of brain), from the official CMS tabular data. D33.2 and D49.6 name the same anatomical site (brain) with a different neoplasm behavior.
Same anatomical site, different neoplasm behavior.
Same site — unspecified behavior (brain)
The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.
Source: CMS Table of Neoplasms
Same site, different neoplasm behavior. D33.2 and D49.6 name the same anatomical site (brain) with a different neoplasm behavior.
From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.
| D33.2Benign neoplasm of brain, unspecified | D49.6Neoplasm of unspecified behavior of brain | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Benign neoplasm of brain, unspecified is a billable ICD-10-CM diagnosis code (D33.2). | Neoplasm of unspecified behavior of brain is a billable ICD-10-CM diagnosis code (D49.6). |
| Includes | — | 'growth' NOS neoplasm NOS new growth NOS tumor NOS |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources