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Compare/D46 vs D61.1

D46 vs D61.1

D46 (Myelodysplastic syndromes) compared with D61.1 (Drug-induced aplastic anemia), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. D46 carries an Excludes2 note covering D61.1: “drug-induced aplastic anemia (D61.1)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

D46Myelodysplastic syndromesD61.1Drug-induced aplastic anemia
Billing statusNon-billable header

Report instead: D46.0, D46.1, D46.20, D46.21, D46.22

Billable
ClassificationC00-D49 — Neoplasms (C00-D49)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionMyelodysplastic syndromes is a non-billable ICD-10-CM category code (D46).Drug-induced aplastic anemia is a billable ICD-10-CM diagnosis code (D61.1).
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources