Skip to main content
Compare/D51 vs E53

D51 vs E53

D51 (Vitamin B12 deficiency anemia) compared with E53 (Deficiency of other B group vitamins), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. D51 carries an Excludes2 note covering E53: “deficiency of other B group vitamins (E53-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

D51Vitamin B12 deficiency anemiaE53Deficiency of other B group vitamins
Billing statusNon-billable header

Report instead: D51.0, D51.1, D51.2, D51.3, D51.8

Non-billable header

Report instead: E53.0, E53.1, E53.8, E53.9

ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionVitamin B12 deficiency anemia is a non-billable ICD-10-CM category code (D51).Deficiency of other B group vitamins is a non-billable ICD-10-CM category code (E53).
Edit this comparisonCheck a whole claim

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources