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ICD-10/E53.8

E53.8 ICD-10-CM Code: Deficiency of other specified B group vitamins

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 640 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITH MCC (MDC 10)
  • MS-DRG 641 — MISCELLANEOUS DISORDERS OF NUTRITION, METABOLISM, FLUIDS AND ELECTROLYTES WITHOUT MCC (MDC 10)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Deficiency of other specified B group vitamins is a billable ICD-10-CM diagnosis code (E53.8).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for E53.8 in the official ICD-10-CM tabular list.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Biotin deficiency
  • Cyanocobalamin deficiency
  • Folate deficiency
  • Folic acid deficiency
  • Pantothenic acid deficiency
  • Vitamin B12 deficiency

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • folate deficiency anemia (D52.-)
  • sequelae of vitamin B deficiency (E64.8)

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • vitamin B12 deficiency anemia (D51.-)
  • nutritional anemias (D50-D53)

Nearest Codes in This Family

Official ICD-10-CM classifications closest to E53.8 in its code family, with their registry titles.

  • E53 — Deficiency of other B group vitamins
  • E53.0 — Riboflavin deficiency
  • E53.1 — Pyridoxine deficiency
  • E53.9 — Vitamin B deficiency, unspecified

View all codes in the E53 family

Indexed Clinical Terms (30)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Acid, deficiency, folic
  • Acid, deficiency, pantothenic
  • Avitaminosis (multiple), B12
  • Chacaleh
  • Deficiency, deficient, biotin
  • Deficiency, deficient, choline
  • Deficiency, deficient, cyanocobalamin
  • Deficiency, deficient, folate
  • Deficiency, deficient, folic acid
  • Deficiency, deficient, inositol (B complex)
  • Deficiency, deficient, pantothenic acid
  • Deficiency, deficient, vitamin NOS (multiple), B12
  • Deficiency, deficient, vitamin NOS (multiple), folic acid
  • Deficiency, deficient, vitamin NOS (multiple), group B, specified NEC
  • Deficiency, deficient, vitamin NOS (multiple), H (biotin)
  • Degeneration, degenerative, brain (cortical) (progressive), in, vitamin B12 deficiency
  • Degeneration, degenerative, combined (spinal cord) (subacute)
  • Degeneration, degenerative, combined (spinal cord) (subacute), in (due to), vitamin B12 deficiency
  • Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), vitamin B12 deficiency
  • Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), in (due to), vitamin B12 deficiency, with behavioral disturbance
  • Electric feet syndrome
  • Lightning (effects) (stroke) (struck by), foot
  • Melalgia, nutritional
  • Myelopathy (spinal cord), vitamin B12
  • Neuropathy, neuropathic, vitamin B12
  • Painful, feet syndrome
  • Polyneuropathy (peripheral), in (due to), vitamin B12 deficiency
  • Syndrome, electric feet
  • Syndrome, Gopalan's (burning feet)
  • Syndrome, painful, feet