D57.218 vs D58
D57.218 (Sickle-cell/Hb-C disease with crisis with other specified complication) compared with D58 (Other hereditary hemolytic anemias), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. D57.218 carries an Excludes1 note covering D58: “other hemoglobinopathies (D58.-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| D57.218Sickle-cell/Hb-C disease with crisis with other specified complication | D58Other hereditary hemolytic anemias | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) | D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) |
| Definition | Sickle-cell/Hb-C disease with crisis with other specified complication is a billable ICD-10-CM diagnosis code (D57.218). | Other hereditary hemolytic anemias is a non-billable ICD-10-CM category code (D58). |
| Use additional code | code to identify complications, such as: cholelithiasis (K80.-) priapism (N48.32) | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources