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Compare/D68.312 vs D68.5

D68.312 vs D68.5

D68.312 (Antiphospholipid antibody with hemorrhagic disorder) compared with D68.5 (Primary thrombophilia), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. D68.5 carries an Excludes1 note covering D68.312: “systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D68.312Antiphospholipid antibody with hemorrhagic disorderD68.5Primary thrombophilia
Billing statusBillableNon-billable header

Report instead: D68.51, D68.52, D68.59

ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionAntiphospholipid antibody with hemorrhagic disorder is a billable ICD-10-CM diagnosis code (D68.312).Primary thrombophilia is a non-billable ICD-10-CM category code (D68.5).
Includes
Lupus anticoagulant (LAC) with hemorrhagic disorder
Systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder
Primary hypercoagulable states

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources