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D69.51 vs T80.59XS

D69.51 (Posttransfusion purpura) compared with T80.59XS (Anaphylactic reaction due to other serum, sequela), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. T80.59XS carries an Excludes2 note covering D69.51: “posttransfusion purpura (D69.51)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

D69.51Posttransfusion purpuraT80.59XSAnaphylactic reaction due to other serum, sequela
Billing statusBillableBillable
ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionPosttransfusion purpura is a billable ICD-10-CM diagnosis code (D69.51).Anaphylactic reaction due to other serum, sequela is a billable ICD-10-CM diagnosis code (T80.59S).
7th characterThe appropriate 7th character is to be added to each code from category T80
Includes
Posttransfusion purpura from whole blood (fresh) or blood products
PTP
complications following perfusion
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources