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D71 vs D89.40

D71 (Functional disorders of polymorphonuclear neutrophils) compared with D89.40 (Mast cell activation, unspecified), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Relationship

Conflict

Excludes1 conflict

D89.40
Mast cell activation, unspecified
D71
Functional disorders of polymorphonuclear neutrophils

Not coded here — these two are mutually exclusive.

“functional disorders of polymorphonuclear neutrophils (D71-)”

An Excludes1 note means the two conditions cannot occur together, so the pair should not be reported for the same encounter. The sole exception is when the conditions are documented as unrelated to each other.

Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a

Can these codes be reported together?

No — do not report together. D89.40 carries an Excludes1 note covering D71: “functional disorders of polymorphonuclear neutrophils (D71-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

D71Functional disorders of polymorphonuclear neutrophilsD89.40Mast cell activation, unspecified
Billing statusNon-billable header

Report instead: D71.1, D71.8, D71.9

Billable
ClassificationD50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionFunctional disorders of polymorphonuclear neutrophils is a non-billable ICD-10-CM category code (D71).Mast cell activation, unspecified is a billable ICD-10-CM diagnosis code (D89.40).
Includes
defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis
Mast cell activation disorder, unspecified

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources