Skip to main content

D71.1 ICD-10-CM Code: Leukocyte adhesion deficiency

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
6 inclusion terms
Risk adjustment
CMS-HCC V28: 1 category · CMS-HCC V22 category 47

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 808 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH MCC (MDC 16)
  • MS-DRG 809 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH CC (MDC 16)
  • MS-DRG 810 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITHOUT CC/MCC (MDC 16)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 115 — Specified Immunodeficiencies and White Blood Cell Disorders

Other models: CMS-HCC V22 HCC 47

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D71.1 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Inclusion Terms

Alternative terms the tabular list files under this code.

  • LAD-I
  • LAD-II
  • LAD-III
  • Leukocyte adhesion deficiency type I
  • Leukocyte adhesion deficiency type II
  • Leukocyte adhesion deficiency type III

Code Overview

Leukocyte adhesion deficiency is a billable ICD-10-CM diagnosis code (D71.1).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (5)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Official Coding Guidelines

No excerpt in the ICD-10-CM Official Guidelines names this code specifically. Its chapter carries only this chapter-wide note:

Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Reserved for future guideline expansion

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name D71.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 8 Excludes1 notes: D80 — Immunodeficiency with predominantly antibody defects (via D71.-), D80-D89 — Certain disorders involving the immune mechanism (D80-D89) (via D71.-), D81 — Combined immunodeficiencies (via D71.-), D82 — Immunodeficiency associated with other major defects (via D71.-), D83 — Common variable immunodeficiency (via D71.-), D84 — Other immunodeficiencies (via D71.-), D86 — Sarcoidosis (via D71.-), D89 — Other disorders involving the immune mechanism, not elsewhere classified (via D71.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 22 Excludes2 notes across 2 chapters: L20 — Atopic dermatitis (via D71.-), L20-L30 — Dermatitis and eczema (L20-L30) (via D71.-), L21 — Seborrheic dermatitis (via D71.-), L22 — Diaper dermatitis (via D71.-), L23 — Allergic contact dermatitis (via D71.-), L24 — Irritant contact dermatitis (via D71.-), L25 — Unspecified contact dermatitis (via D71.-), L26 — Exfoliative dermatitis (via D71.-), L27 — Dermatitis due to substances taken internally (via D71.-), L28 — Lichen simplex chronicus and prurigo (via D71.-), L29 — Pruritus (via D71.-), L30 — Other and unspecified dermatitis (via D71.-), R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity (via D71.-), R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79) (via D71.-), R71 — Abnormality of red blood cells (via D71.-), R73 — Elevated blood glucose level (via D71.-), R74 — Abnormal serum enzyme levels (via D71.-), R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV] (via D71.-), R76 — Other abnormal immunological findings in serum (via D71.-), R77 — Other abnormalities of plasma proteins (via D71.-), +2 more.

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 21 Code First instructions: T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics (via D71.-), T36-T39 — Antibiotics & Anti-infectives (T36-T39) (via D71.-), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50) (via D71.-), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (via D71.-), T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (via D71.-), T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (via D71.-), T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] (via D71.-), T40-T41 — Analgesics & Antipyretics (T40-T41) (via D71.-), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (via D71.-), T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (via D71.-), T42-T43 — Anticonvulsants & Psychotropics (T42-T43) (via D71.-), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (via D71.-), T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (via D71.-), T44-T46 — Cardiovascular & Gastrointestinal (T44-T46) (via D71.-), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (via D71.-), T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system (via D71.-), T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (via D71.-), T47-T50 — Hormones & Systemic Agents (T47-T50) (via D71.-), T48 — Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (via D71.-), T49 — Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (via D71.-), +1 more.

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 3 MS-DRGs: DRG 808 (MDC 16), DRG 809 (MDC 16), DRG 810 (MDC 16).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):BLD007 — Diseases of white blood cells (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Specified Immunodeficiencies and White Blood Cell Disorders) for risk-adjusted payment.

D70.0 — Congenital agranulocytosis, D70.4 — Cyclic neutropenia, D71 — Functional disorders of polymorphonuclear neutrophils, D71.8 — Other functional disorders of polymorphonuclear neutrophils, D71.9 — Functional disorders of polymorphonuclear neutrophils, unspecified, D72.0 — Genetic anomalies of leukocytes, D76.1 — Hemophagocytic lymphohistiocytosis, D76.3 — Other histiocytosis syndromes, D80.0 — Hereditary hypogammaglobulinemia, D80.2 — Selective deficiency of immunoglobulin A [IgA], D80.3 — Selective deficiency of immunoglobulin G [IgG] subclasses, D80.4 — Selective deficiency of immunoglobulin M [IgM], D80.5 — Immunodeficiency with increased immunoglobulin M [IgM], D81.4 — Nezelof's syndrome, D82.0 — Wiskott-Aldrich syndrome, D82.1 — Di George's syndrome, D84.1 — Defects in the complement system, D89.84 — IgG4-related disease

Related risk categories

These categories interact through CMS's HCC hierarchy — one can suppress the other's risk-adjustment weight when both are present on a claim.

Common Variable and Combined Immunodeficiencies

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Diseases of white blood cells).

D70.0 — Congenital agranulocytosis, D70.1 — Agranulocytosis secondary to cancer chemotherapy, D70.2 — Other drug-induced agranulocytosis, D70.3 — Neutropenia due to infection, D70.4 — Cyclic neutropenia, D70.8 — Other neutropenia, D70.9 — Neutropenia, unspecified, D71 — Functional disorders of polymorphonuclear neutrophils, D71.8 — Other functional disorders of polymorphonuclear neutrophils, D71.9 — Functional disorders of polymorphonuclear neutrophils, unspecified, D72.0 — Genetic anomalies of leukocytes, D72.1 — Eosinophilia, D72.10 — Eosinophilia, unspecified, D72.110 — Idiopathic hypereosinophilic syndrome [IHES], D72.111 — Lymphocytic Variant Hypereosinophilic Syndrome [LHES], D72.118 — Other hypereosinophilic syndrome, D72.119 — Hypereosinophilic syndrome [HES], unspecified, D72.12 — Drug rash with eosinophilia and systemic symptoms syndrome, D72.18 — Eosinophilia in diseases classified elsewhere, D72.19 — Other eosinophilia, +17 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Deficiency, deficient”; these codes share that main term but sit in a different category of the Tabular List.

D67 — Hereditary factor IX deficiency (PTC), D68.01 — Von Willebrand disease, type 1 (von Willebrand factor, partial quantitative), D68.03 — Von Willebrand disease, type 3 (von Willebrand factor, total quantitative), D68.1 — Hereditary factor XI deficiency (PTA), D68.2 — Hereditary deficiency of other clotting factors (SPCA), D68.4 — Acquired coagulation factor deficiency (AC globulin, acquired), D68.59 — Other primary thrombophilia (protein, S), D68.8 — Other specified coagulation defects (factor, multiple), D68.9 — Coagulation defect, unspecified (clotting), D69.19 — Other qualitative platelet defects (platelet NEC), D74.0 — Congenital methemoglobinemia (NADH diaphorase or reductase), D75.A — Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia (glucose-6-phosphate dehydrogenase, without anemia), D80.0 — Hereditary hypogammaglobulinemia (gammaglobulin in blood, hereditary), D80.1 — Nonfamilial hypogammaglobulinemia (gammaglobulin in blood), D80.2 — Selective deficiency of immunoglobulin A [IgA] (immunity, IgA), D80.3 — Selective deficiency of immunoglobulin G [IgG] subclasses (immunity, IgG), D80.4 — Selective deficiency of immunoglobulin M [IgM] (immunity, IgM), D80.6 — Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia (antibody with, hyperimmunoglobulinemia), D80.8 — Other immunodeficiencies with predominantly antibody defects (kappa-light chain), D80.9 — Immunodeficiency with predominantly antibody defects, unspecified (immunity, humoral), +174 more

Contextual Map

Every relationship of D71.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run D71.1 with these 24 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes

Referenced by Excludes2 notes (22)

  • L20 — Atopic dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L20-L30 — Dermatitis and eczema (L20-L30)[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L21 — Seborrheic dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L22 — Diaper dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L23 — Allergic contact dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L24 — Irritant contact dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L25 — Unspecified contact dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • L26 — Exfoliative dermatitis[Excludes2](via D71.-): “chronic (childhood) granulomatous disease (D71-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • and 14 more

Referenced by Code First instructions (21)

Clinical classification (CCSR)

Risk adjustment (CMS-HCC)

  • HCC 115 — Specified Immunodeficiencies and White Blood Cell Disorders [CMS-HCC]— CMS-HCC V28 · 2026

MS-DRG Grouper

MDC crossing

  • MDC 16 — Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders[MDC crossing]: “Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,614 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Deficiency, deficient, leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Deficiency, deficient, leukocyte adhesion (LAD-I) (LAD-II) (LAD-III), type I[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Deficiency, deficient, leukocyte adhesion (LAD-I) (LAD-II) (LAD-III), type II[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Deficiency, deficient, leukocyte adhesion (LAD-I) (LAD-II) (LAD-III), type III[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • LAD (leukocyte adhesion deficiency) (LAD-I) (LAD-II) (LAD-III)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes

Change history

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Coding guidelines Official source data
ICD-10-CM Official Guidelines for Coding and Reporting (FY2026), quoted by section Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Risk adjustment Official source data
2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "D71.1 — Leukocyte adhesion deficiency." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/d71.1-leukocyte-adhesion-deficiency

Change history

  • FY2026 — October 1, 2025
    Added to the code set
    Leukocyte adhesion deficiency
    FY2026 changes

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D71.1 in its code family, with their registry titles.

View all codes in the D71 family