Name: Eosinophilia
Creator: MedCoder.ai

Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.

Coding at a Glance

Tabular directives: 3 Excludes1 · 3 Excludes2

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D72.1 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on D72.1 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

basophilia (D72.824) Compare D72.1 vs D72.824 →
immunity disorders (D80-D89) Compare D72.1 vs D80 →
preleukemia (syndrome) (D46.9) Compare D72.1 vs D46.9 →

Source: inherited from D72

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Löffler's syndrome (J82.89) Compare D72.1 vs J82.89 →
pulmonary eosinophilia (J82.-) Compare D72.1 vs J82 →
neutropenia (D70) inherited from D72Compare D72.1 vs D70 →

Coder workflow for D72.1

MedCoder structured workflow — derived from this code’s own official record

Before you code D72.1

D72.1 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewD72.10, D72.11, D72.12, D72.18, D72.19
See the relationships section · Guide: How to choose an ICD-10-CM code →
Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with D72.1. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
See the official tabular notes

Choose the right path

Does the documentation support one of the more specific codes beneath D72.1?
Yes → Select that code and continue the checks below on its own page.
No → D72.1 cannot be reported as written; query for the specificity its subcategory needs.
ReviewD72.10, D72.11, D72.12, D72.18, D72.19
Does the documentation support a condition named in D72.1’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
ReviewD72.824, D46.9

Consider D72.1. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement: Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Official instructions as workflow

Excludes1 — check before selecting D72.1(3 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with D72.1: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareD72.824, D46.9
See the official tabular notes · Guidelines I.A.12.a
Excludes2 — not part of D72.1(3 notes)
Coding workflow: The conditions named in this note are not included in D72.1. When the record documents both, both may be reported; the note is a boundary, not a prohibition.
CompareJ82.89, J82, D70
See the official tabular notes · Guidelines I.A.12.b

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition D72.1 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewD72.824, D46.9

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Eosinophilia is a non-billable ICD-10-CM category code (D72.1). A more specific billable subcode must be selected for claims submission.

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Don’t confuse D72.1 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of D72.1 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

D72.824— Excludes1 conflict (Excludes1 — generally not reported together)
Not coded here — the tabular list excludes this pair for the same encounter.
Not reported together with this code, except where the two conditions are documented as unrelated.
What moves you there: Documentation of basophilia moves the case to D72.824; the two are not reported together unless documented as unrelated.
Full comparison: D72.1 vs D72.824 →
D80— Excludes1 conflict (Excludes1 — generally not reported together)
Not coded here — the tabular list excludes this pair for the same encounter.
Not reported together with this code, except where the two conditions are documented as unrelated.
What moves you there: Documentation of immunity disorders moves the case to D80; the two are not reported together unless documented as unrelated.
Full comparison: D72.1 vs D80 →
D89— Excludes1 conflict (Excludes1 — generally not reported together)
Not coded here — the tabular list excludes this pair for the same encounter.
Not reported together with this code, except where the two conditions are documented as unrelated.
What moves you there: Documentation of immunity disorders moves the case to D89; the two are not reported together unless documented as unrelated.
Full comparison: D72.1 vs D89 →
D46.9— Excludes1 conflict (Excludes1 — generally not reported together)
Not coded here — the tabular list excludes this pair for the same encounter.
Not reported together with this code, except where the two conditions are documented as unrelated.
What moves you there: Documentation of preleukemia (syndrome) moves the case to D46.9; the two are not reported together unless documented as unrelated.
Full comparison: D72.1 vs D46.9 →
D72.9— Specificity relationship (Review)
Overlapping diagnoses in the same category.
Overlapping codes in the same category — the documentation decides which is the more specific fit.
What moves you there: A record that documents no more than “Disorder of white blood cells, unspecified” takes D72.9; specificity in the record moves it back here.
Full comparison: D72.1 vs D72.9 →
J82.89— Excludes2 relationship (Informational)
Distinct conditions — both may be reported.
A distinct condition — both may be reported when both are documented.
What moves you there: Documentation of Löffler's syndrome adds J82.89; it is not part of this code and both may be reported when both are documented.
Full comparison: D72.1 vs J82.89 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Verify Before Coding

Not billable as written — a more specific code is required: D72.10, D72.110, D72.111, D72.118, D72.119.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name D72.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: D72.82 — Elevated white blood cell count.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 10 Excludes2 notes: R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity (via D72.-), R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79) (via D72.-), R71 — Abnormality of red blood cells (via D72.-), R73 — Elevated blood glucose level (via D72.-), R74 — Abnormal serum enzyme levels (via D72.-), R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV] (via D72.-), R76 — Other abnormal immunological findings in serum (via D72.-), R77 — Other abnormalities of plasma proteins (via D72.-), R78 — Findings of drugs and other substances, not normally found in blood (via D72.-), R79 — Other abnormal findings of blood chemistry (via D72.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Referenced by 1 Code Also instruction: D47.02 — Systemic mastocytosis.

These codes suggest coding this condition alongside when both are present.

Clinical classification (AHRQ CCSR):BLD007 — Diseases of white blood cells (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Diseases of white blood cells).

D70.2 — Other drug-induced agranulocytosis, D70.3 — Neutropenia due to infection, D70.4 — Cyclic neutropenia, D70.8 — Other neutropenia, D70.9 — Neutropenia, unspecified, D71 — Functional disorders of polymorphonuclear neutrophils, D71.1 — Leukocyte adhesion deficiency, D71.8 — Other functional disorders of polymorphonuclear neutrophils, D71.9 — Functional disorders of polymorphonuclear neutrophils, unspecified, D72.0 — Genetic anomalies of leukocytes, D72.10 — Eosinophilia, unspecified, D72.110 — Idiopathic hypereosinophilic syndrome [IHES], D72.111 — Lymphocytic Variant Hypereosinophilic Syndrome [LHES], D72.118 — Other hypereosinophilic syndrome, D72.119 — Hypereosinophilic syndrome [HES], unspecified, D72.12 — Drug rash with eosinophilia and systemic symptoms syndrome, D72.18 — Eosinophilia in diseases classified elsewhere, D72.19 — Other eosinophilia, D72.810 — Lymphocytopenia, D72.818 — Other decreased white blood cell count, +17 more

Contextual Map

Every relationship of D72.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run D72.1 with these 20 related codes in Claim Check

Hierarchy

D50-D89 — Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) (D50-D89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D70-D77 — Other disorders of blood and blood-forming organs[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Excludes2

J82 — Pulmonary eosinophilia, not elsewhere classified[Excludes2]: “pulmonary eosinophilia (J82.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
J82.89 — Other pulmonary eosinophilia, not elsewhere classified[Excludes2]: “Löffler's syndrome (J82.89)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes1 notes

D72.82 — Elevated white blood cell count[Excludes1]: “eosinophilia (D72.1)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes (10)

R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79)[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R71 — Abnormality of red blood cells[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R73 — Elevated blood glucose level[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R74 — Abnormal serum enzyme levels[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV][Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R76 — Other abnormal immunological findings in serum[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
R77 — Other abnormalities of plasma proteins[Excludes2](via D72.-): “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
and 2 more

Referenced by Code First instructions (21)

T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T36-T39 — Antibiotics & Anti-infectives (T36-T39)[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens][Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
T40-T41 — Analgesics & Antipyretics (T40-T41)[Code First](via D72.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
and 13 more

Referenced by Code Also instructions

D47.02 — Systemic mastocytosis[Code Also]: “hypereosinophilic syndrome (D72.1)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Clinical classification (CCSR)

BLD007 — Diseases of white blood cells[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

Nearest codes (27)

D72 — Other disorders of white blood cells[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.0 — Genetic anomalies of leukocytes[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.10 — Eosinophilia, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.11 — Hypereosinophilic syndrome [HES][Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.110 — Idiopathic hypereosinophilic syndrome [IHES][Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.111 — Lymphocytic Variant Hypereosinophilic Syndrome [LHES][Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.118 — Other hypereosinophilic syndrome[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
D72.119 — Hypereosinophilic syndrome [HES], unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
and 19 more

Change history (2)

FY2021 — Became a non-billable header[Change history]— CMS release files (code change ledger) · icd10cm-fy2021
and 1 more

Common coding questions

Can D72.1 be billed directly?

No. D72.1 (Eosinophilia) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data: CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data: CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data: CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship: Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation: Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "D72.1 — Eosinophilia." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/d72.1-eosinophilia

Change history

FY2021 — October 1, 2020
Became a non-billable header
FY2021 changes
FY2016 — October 1, 2015
In the code set at ICD-10-CM adoption
Eosinophilia

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D72.1 in its code family, with their registry titles.

View all codes in the D72 family

D72.1 ICD-10-CM Code: Eosinophilia