D70 ICD-10-CM Code: Neutropenia
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coding at a Glance
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D70 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- agranulocytosis
- decreased absolute neurophile count (ANC)
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- neutropenic splenomegaly (D73.81) Compare D70 vs D73.81 →
- transient neonatal neutropenia (P61.5) Compare D70 vs P61.5 →
Code Also
Additional codes that may be required to fully describe the encounter.
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code for any associated:
- fever (R50.81)
Coder workflow for D70
MedCoder structured workflow — derived from this code’s own official record
Before you code D70
- D70 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewD70.0, D70.1, D70.2, D70.3, D70.4, D70.8, D70.9
See the relationships section · Guide: How to choose an ICD-10-CM code →
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with D70. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support one of the more specific codes beneath D70?
Yes → Select that code and continue the checks below on its own page.
No → D70 cannot be reported as written; query for the specificity its subcategory needs. - Does the documentation support a condition named in D70’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Consider D70. Then work the Use Additional Code note and review the Code Also note, and confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- The conditions the Use Additional Code note names
- Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.
Official instructions as workflow
Excludes1 — check before selecting D70(2 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with D70: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
See the official tabular notes · Guidelines I.A.12.a
Use Additional Code — after identifying D70(2 notes)
Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with D70 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.
ReviewR50.81
See the official tabular notes · Guidelines I.A.13
Code Also — related condition(1 note)
Coding workflow: Review the related condition when both are documented and the instruction applies. A Code Also note does not fix sequencing; the order follows the circumstances of the encounter.
ReviewJ34.81, K12.3, K92.81, N76.81
See the official tabular notes · Guidelines I.A.17
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition D70 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Documentation: A condition the Use Additional Code note names is documented.
Coding question: Is a second code reported with D70?
Path: Review the Use Additional Code note and the code it names.
Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).
ReviewR50.81
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Decision Points
The directives on this code's own record, as a pre-claim checklist.
- 2 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
- 1 Code Also note — a second code may apply; the guidelines leave its sequencing to the circumstances of the encounter. See the Code Also notes
- 2 Excludes1 entries — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name D70 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 12 Excludes2 notes across 2 chapters: D61 — Other aplastic anemias and other bone marrow failure syndromes, D72 — Other disorders of white blood cells, R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity, R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79), R71 — Abnormality of red blood cells, R73 — Elevated blood glucose level, R74 — Abnormal serum enzyme levels, R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV], R76 — Other abnormal immunological findings in serum, R77 — Other abnormalities of plasma proteins, R78 — Findings of drugs and other substances, not normally found in blood, R79 — Other abnormal findings of blood chemistry.
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
Referenced by 22 Code First instructions across 2 chapters: R50.81 — Fever presenting with conditions classified elsewhere, T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics, T36-T39 — Antibiotics & Anti-infectives (T36-T39), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics, T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified, T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics, T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens], T40-T41 — Analgesics & Antipyretics (T40-T41), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases, T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs, T42-T43 — Anticonvulsants & Psychotropics (T42-T43), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified, T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system, T44-T46 — Cardiovascular & Gastrointestinal (T44-T46), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified, T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system, T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system, T47-T50 — Hormones & Systemic Agents (T47-T50), T48 — Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system, +2 more.
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Contextual Map
Every relationship of D70 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run D70 with these 22 related codes in Claim Check
Hierarchy
- D50-D89 — Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) (D50-D89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70-D77 — Other disorders of blood and blood-forming organs[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Excludes1
- D73.81 — Neutropenic splenomegaly[Excludes1]: “neutropenic splenomegaly (D73.81)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- P61.5 — Transient neonatal neutropenia[Excludes1]: “transient neonatal neutropenia (P61.5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Use Additional Code
- R50.81 — Fever presenting with conditions classified elsewhere[Use Additional Code]: “fever (R50.81)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Code Also
- J34.81 — Nasal mucositis (ulcerative)[Code Also]: “, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- K12.3 — Oral mucositis (ulcerative)[Code Also]: “, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- K92.81 — Gastrointestinal mucositis (ulcerative)[Code Also]: “, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- N76.81 — Mucositis (ulcerative) of vagina and vulva[Code Also]: “, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes (12)
- D61 — Other aplastic anemias and other bone marrow failure syndromes[Excludes2]: “neutropenia (D70.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- D72 — Other disorders of white blood cells[Excludes2]: “neutropenia (D70)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity[Excludes2]: “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79)[Excludes2]: “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R71 — Abnormality of red blood cells[Excludes2]: “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R73 — Elevated blood glucose level[Excludes2]: “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R74 — Abnormal serum enzyme levels[Excludes2]: “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV][Excludes2]: “abnormalities of white blood cells classified elsewhere (D70-D72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 4 more
Referenced by Code First instructions (22)
- R50.81 — Fever presenting with conditions classified elsewhere[Code First]: “neutropenia (D70.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36-T39 — Antibiotics & Anti-infectives (T36-T39)[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens][Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 14 more
Nearest codes
- D70.0 — Congenital agranulocytosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70.1 — Agranulocytosis secondary to cancer chemotherapy[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70.2 — Other drug-induced agranulocytosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70.3 — Neutropenia due to infection[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70.4 — Cyclic neutropenia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70.8 — Other neutropenia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D70.9 — Neutropenia, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can D70 be billed directly?
No. D70 (Neutropenia) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "D70 — Neutropenia." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/d70-neutropenia
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionNeutropenia
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to D70 in its code family, with their registry titles.