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ICD-10/D70.1

D70.1 ICD-10-CM Code: Agranulocytosis secondary to cancer chemotherapy

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 808 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH MCC (MDC 16)
  • MS-DRG 809 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH CC (MDC 16)
  • MS-DRG 810 — MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITHOUT CC/MCC (MDC 16)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Agranulocytosis secondary to cancer chemotherapy is a billable ICD-10-CM diagnosis code (D70.1).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for D70.1 in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • agranulocytosis
  • decreased absolute neurophile count (ANC)

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • neutropenic splenomegaly (D73.81)
  • transient neonatal neutropenia (P61.5)

Code Also

Additional codes that may be required to fully describe the encounter.

  • underlying neoplasm
  • Code also, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code for adverse effect, if applicable, to identify drug (T45.1X5)
  • Use additional code for any associated:
  • fever (R50.81)

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D70.1 in its code family, with their registry titles.

  • D70 — Neutropenia
  • D70.0 — Congenital agranulocytosis
  • D70.2 — Other drug-induced agranulocytosis
  • D70.3 — Neutropenia due to infection
  • D70.4 — Cyclic neutropenia
  • D70.8 — Other neutropenia
  • D70.9 — Neutropenia, unspecified

View all codes in the D70 family

Indexed Clinical Terms (8)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Agranulocytosis (chronic) (cyclical) (genetic) (infantile) (periodic) (pernicious), cytoreductive cancer chemotherapy sequela
  • Agranulocytosis (chronic) (cyclical) (genetic) (infantile) (periodic) (pernicious), drug-induced, due to cytoreductive cancer chemotherapy
  • Agranulocytosis (chronic) (cyclical) (genetic) (infantile) (periodic) (pernicious), secondary, drug-induced, due to cytoreductive cancer chemotherapy
  • Leukopenia, chemotherapyinduced (cancer)
  • Leukopenia, drug induced NEC, due to cytoreductive cancer chemotherapy
  • Neutropenia, neutropenic (chronic) (genetic) (idiopathic) (immune) (infantile) (malignant) (pernicious) (splenic), cytoreductive cancer chemotherapy sequela
  • Neutropenia, neutropenic (chronic) (genetic) (idiopathic) (immune) (infantile) (malignant) (pernicious) (splenic), drug-induced, due to cytoreductive cancer chemotherapy
  • Neutropenia, neutropenic (chronic) (genetic) (idiopathic) (immune) (infantile) (malignant) (pernicious) (splenic), secondary (cyclic) (periodic) (splenic), drug-induced, due to cytoreductive cancer chemotherapy