E05.8 vs E22
E05.8 (Other thyrotoxicosis) compared with E22 (Hyperfunction of pituitary gland), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. E22 carries an Excludes1 note covering E05.8: “overproduction of thyroid-stimulating hormone (E05.8-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| E05.8Other thyrotoxicosis | E22Hyperfunction of pituitary gland | |
|---|---|---|
| Billing status | Non-billable header | Non-billable header |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) |
| Definition | Other thyrotoxicosis is a non-billable ICD-10-CM category code (E05.8). | Hyperfunction of pituitary gland is a non-billable ICD-10-CM category code (E22). |
| Includes | Overproduction of thyroid-stimulating hormone | — |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources