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E11.3542 vs E11.3543

E11.3542 (Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, left eye) compared with E11.3543 (Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, bilateral), from the official CMS tabular data.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Summary

These codes name the same condition on one side and on both sides, so when both sides are documented the bilateral code applies rather than a code for each side.

MedCoder-derived
What is different?

Title wording.The titles share “Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment”; E11.3542 says “left eye” where E11.3543 says “bilateral”.

Registry fact

Can these codes be reported together?

One code for both sides.E11.3542 and E11.3543 name the same condition on one side and on both sides. When the condition is documented on both sides and the code set provides a bilateral code, the bilateral code is assigned rather than a code for each side (ICD-10-CM Official Guidelines, Section I.B.13).

MedCoder-derivedGuide: Laterality coding

Are there other coding relationships?

Yes.Same condition; one side or both sides. E11.3542 and E11.3543 name the same condition on one side and on both sides.

MedCoder-derivedGuide: Laterality coding

Nothing found in 5 other checks
Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code. E11.3542 carries 8 Excludes1 notes and E11.3543 carries 8 Excludes1 notes covering other codes; the side-by-side table quotes them.

Official rule

Is there an Excludes2 relationship?

None.Neither entry carries an Excludes2 note that names the other code.

Official rule

Is one more specific?

No.Neither is a subdivision of the other, and neither title is the unspecified form; they describe different conditions within category E11.

Registry fact

Is one a parent or header code?

No.Both are billable codes, and neither contains the other.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Review

Laterality relationship

E11.3542
Left
Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, left eye
↔
E11.3543
Bilateral
Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, bilateral

What we found

Same condition; one side or both sides.E11.3542 and E11.3543 name the same condition on one side and on both sides.

When the condition is documented on both sides and the code set provides a bilateral code, the bilateral code is assigned rather than a code for each side (ICD-10-CM Official Guidelines, Section I.B.13).

What to review

Report the side the documentation names. Where the code set provides a bilateral code and both sides are documented, use it instead of the pair.

Guide: Laterality codingCheck these on a claim

Why it matters

These codes share a category and title and differ only in the side affected. The documentation decides which applies, and a bilateral code is reported only where the code set provides one.

Source / rule

ICD-10-CM tabular list (laterality variant derived from the code title)

Official guidance behind these answers

  • Section I.B.13 — Laterality · applies to: Laterality

    Some ICD-10-CM codes indicate laterality, specifying whether the condition occurs on the left, right or is bilateral. If no bilateral code is provided and the condition is bilateral, assign separate codes for both the left and right side. If the side is not identified in the medical record, assign the code for the unspecified side. When a patient has a bilateral condition and each side is treated during separate encounters, assign the "bilateral" code (as the condition still exists on both sides), including for the encounter to treat the first side. For the second encounter for treatment after one side has previously been treated and the condition no longer exists on that side, assign the appropriate unilateral code for the side where the condition still exists (e.g., cataract surgery performed on each eye in separate encounters). The bilateral code would not be assigned for the subsequent encounter, as the patient no longer has the condition in the previously-treated site. If the treatment on the first side did not completely resolve the condition, then the bilateral code would still be appropriate. When laterality is not documented by the patient’s provider, code assignment for the affected side may be based on medical record documentation from other clinicians. If there is conflicting medical record documentation regarding the affected side, the patient’s provider should be queried for clarification. […]

    ICD-10-CM Official Guidelines FY2027

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

Similar descriptions do not make codes interchangeable. The documentation and the official instructions decide which code applies.

Official descriptionDiffers
E11.3542

Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, left eye

E11.3543

Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, bilateral

StatusSame for both
Billable
Excludes1Same for both
  • diabetes mellitus due to underlying condition (E08.-)
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 1 diabetes mellitus (E10.-)
Use additional codeSame for both
  • code to identify control using:
  • injectable non-insulin antidiabetic drugs (Z79.85)
  • insulin (Z79.4)
  • oral antidiabetic drugs (Z79.84)
  • oral hypoglycemic drugs (Z79.84)
CategorySame for both

E11 Type 2 diabetes mellitus

ChapterSame for both

E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)

IncludesSame for both
  • diabetes (mellitus) due to insulin secretory defect
  • diabetes NOS
  • insulin resistant diabetes (mellitus)
7th characterSame for both
  • One of the following 7th characters is to be assigned to codes in subcategory E11.35 to designate laterality of the disease:

No Excludes2, Code first and Code also note at either code.

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on. In a row that differs, each code’s own notes are listed under it, and the notes every code shares are listed once beneath them.

Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources