E21 vs E83.52
E21 (Hyperparathyroidism and other disorders of parathyroid gland) compared with E83.52 (Hypercalcemia), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
Yes, when both are documented. E21 carries an Excludes2 note covering E83.52: “familial hypocalciuric hypercalcemia (E83.52)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
No — do not report together. E83.52 carries an Excludes1 note covering E21: “parathyroid disorders (E20-E21)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| E21Hyperparathyroidism and other disorders of parathyroid gland | E83.52Hypercalcemia | |
|---|---|---|
| Billing status | Non-billable header | Billable |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) |
| Definition | Hyperparathyroidism and other disorders of parathyroid gland is a non-billable ICD-10-CM category code (E21). | Hypercalcemia is a billable ICD-10-CM diagnosis code (E83.52). |
| Includes | — | Familial hypocalciuric hypercalcemia |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources