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Compare/E25 vs E30.1

E25 vs E30.1

E25 (Adrenogenital disorders) compared with E30.1 (Precocious puberty), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E30.1 carries an Excludes1 note covering E25: “female heterosexual precocious pseudopuberty (E25.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. E30.1 carries an Excludes1 note covering E25: “male isosexual precocious pseudopuberty (E25.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E25Adrenogenital disordersE30.1Precocious puberty
Billing statusNon-billable header

Report instead: E25.0, E25.8, E25.9

Billable
ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)
DefinitionAdrenogenital disorders is a non-billable ICD-10-CM category code (E25).Precocious puberty is a billable ICD-10-CM diagnosis code (E30.1).
Includes
adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
Female adrenal pseudohermaphroditism
Female heterosexual precocious pseudopuberty
Male isosexual precocious pseudopuberty
Precocious menstruation

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources