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Compare/E25 vs Q99

E25 vs Q99

E25 (Adrenogenital disorders) compared with Q99 (Other chromosome abnormalities, not elsewhere classified), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. E25 carries an Excludes1 note covering Q99: “chromosomal abnormalities (Q90-Q99)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E25Adrenogenital disordersQ99Other chromosome abnormalities, not elsewhere classified
Billing statusNon-billable header

Report instead: E25.0, E25.8, E25.9

Non-billable header

Report instead: Q99.0, Q99.1, Q99.2, Q99.811, Q99.812

ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)Q00-Q99 — Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99)
DefinitionAdrenogenital disorders is a non-billable ICD-10-CM category code (E25).Other chromosome abnormalities, not elsewhere classified is a non-billable ICD-10-CM category code (Q99).
Includes
adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
Female adrenal pseudohermaphroditism
Female heterosexual precocious pseudopuberty
Male isosexual precocious pseudopuberty

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources