E78 vs E88.0
E78 (Disorders of lipoprotein metabolism and other lipidemias) compared with E88.0 (Disorders of plasma-protein metabolism, not elsewhere classified), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. E88.0 carries an Excludes2 note covering E78: “disorder of lipoprotein metabolism (E78.-)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| E78Disorders of lipoprotein metabolism and other lipidemias | E88.0Disorders of plasma-protein metabolism, not elsewhere classified | |
|---|---|---|
| Billing status | Non-billable header | Non-billable header |
| Classification | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) | E00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89) |
| Definition | Disorders of lipoprotein metabolism and other lipidemias is a non-billable ICD-10-CM category code (E78). | Disorders of plasma-protein metabolism, not elsewhere classified is a non-billable ICD-10-CM category code (E88.0). |
| Use additional code | — | codes for associated conditions |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources