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Compare/E80.4 vs P53

E80.4 vs P53

E80.4 (Gilbert syndrome) compared with P53 (Hemorrhagic disease of newborn), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. P53 carries an Excludes1 note covering E80.4: “Gilbert syndrome (E80.4)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

E80.4Gilbert syndromeP53Hemorrhagic disease of newborn
Billing statusBillableBillable
ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)P00-P96 — Certain Conditions Originating in the Perinatal Period (P00-P96)
DefinitionGilbert syndrome is a billable ICD-10-CM diagnosis code (E80.4).Hemorrhagic disease of newborn is a billable ICD-10-CM diagnosis code (P53).
Includes
defects of catalase and peroxidase
Vitamin K deficiency of newborn

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources