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E86 vs T80.30XA

E86 (Volume depletion) compared with T80.30XA (ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. T80.30XA carries an Excludes2 note covering E86: “disorders of fluid and electrolyte imbalance (E86-E87)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

E86Volume depletionT80.30XAABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
Billing statusNon-billable header

Report instead: E86.0, E86.1, E86.9

Billable
ClassificationE00-E89 — Endocrine, Nutritional and Metabolic Diseases (E00-E89)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionVolume depletion is a non-billable ICD-10-CM category code (E86).ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter is a billable ICD-10-CM diagnosis code (T80.30A).
7th characterThe appropriate 7th character is to be added to each code from category T80
Includes
complications following perfusion
ABO incompatibility blood transfusion NOS
Reaction to ABO incompatibility from transfusion NOS
Use additional code
code(s) for any associated disorders of electrolyte and acid-base balance (E87.-)
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources