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Compare/F07.0 vs R45

F07.0 vs R45

F07.0 (Personality change due to known physiological condition) compared with R45 (Symptoms and signs involving emotional state), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. F07.0 carries an Excludes1 note covering R45: “signs and symptoms involving emotional state (R45.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

F07.0Personality change due to known physiological conditionR45Symptoms and signs involving emotional state
Billing statusBillableNon-billable header

Report instead: R45.0, R45.1, R45.2, R45.3, R45.4

ClassificationF01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)
DefinitionPersonality change due to known physiological condition is a billable ICD-10-CM diagnosis code (F07.0).Symptoms and signs involving emotional state is a non-billable ICD-10-CM category code (R45).
Includes
Frontal lobe syndrome
Limbic epilepsy personality syndrome
Lobotomy syndrome
Organic personality disorder
Code first
the underlying physiological condition

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources