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F14.221 vs F15

F14.221 (Cocaine dependence with intoxication delirium) compared with F15 (Other stimulant related disorders), from the official CMS tabular data.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Summary

These codes can be reported together when both conditions are documented, because F14.221 lists F15 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

The conditions named and billing status.F14.221 is “Cocaine dependence with intoxication delirium”; F15 is “Other stimulant related disorders”. F15 is a non-billable header; F14.221 is billable.

Registry fact

Can these codes be reported together?

Yes, when both are documented.F14.221 lists F15 under Excludes2: “other stimulant-related disorders (F15.-)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code. F14.221 carries 3 Excludes1 notes covering other codes; the side-by-side table quotes them.

Official rule

Is there an Excludes2 relationship?

Yes.F14.221’s tabular entry: “other stimulant-related disorders (F15.-)”. The note covers F15.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

Not comparable.The codes sit in different categories; specificity is only comparable within one category.

Is one a parent or header code?

One is a header.F15 is a non-billable header, but F14.221 is not one of its subdivisions.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

F14.221
Cocaine dependence with intoxication delirium
↔
F15
Other stimulant related disorders

What we found

Yes, when both are documented.F14.221 carries an Excludes2 note covering F15: “other stimulant-related disorders (F15.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2027

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

Similar descriptions do not make codes interchangeable. The documentation and the official instructions decide which code applies.

Official descriptionDiffers
F14.221

Cocaine dependence with intoxication delirium

F15

Other stimulant related disorders

StatusDiffers
F14.221
Billable
F15
Non-billable header

A header is not reported on a claim; a code beneath it is.

Report instead: F15.10, F15.11, F15.120, F15.121, F15.122

Excludes1Differs
F14.221
  • cocaine dependence with withdrawal (F14.23)
  • cocaine abuse (F14.1-)
  • cocaine use, unspecified (F14.9-)
F15

None at this code

Excludes2Differs
F14.221
  • cocaine poisoning (T40.5-)
  • other stimulant-related disorders (F15.-)
F15
  • cocaine-related disorders (F14.-)
CategoryDiffers
F14.221

F14 Cocaine related disorders

F15

Is itself a category

ChapterSame for both

F01-F99 — Mental, Behavioral and Neurodevelopmental Disorders (F01-F99)

IncludesDiffers
F14.221

None at this code

F15
  • amphetamine-related disorders
  • caffeine

No Code first, Use additional code, Code also and 7th character note at either code.

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on. In a row that differs, notes every code shares are dimmed.

Edit this comparisonCheck a whole claim

Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources