Sequencing relationship
What we found
Sequence I21 before Z92.82
I21 carries a Use Additional Code instruction covering Z92.82: “status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)”
Z92.82 carries a Code First instruction covering I21: “acute myocardial infarction (I21.-, I22.-)”
What to review
On a claim that carries both, list I21 ahead of Z92.82; the manifestation is never the principal diagnosis.
Why it matters
A "Code first" note means the underlying etiology is sequenced ahead of this manifestation code on the claim.
Source / rule
CMS ICD-10-CM tabular instructional notes