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I25.1 vs I70.229

I25.1 (Atherosclerotic heart disease of native coronary artery) compared with I70.229 (Atherosclerosis of native arteries of extremities with rest pain, unspecified extremity), from the official CMS tabular data.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Summary

These codes can be reported together when both conditions are documented, because I70.229 lists I25.1 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

The conditions named and billing status.I25.1 is “Atherosclerotic heart disease of native coronary artery”; I70.229 is “Atherosclerosis of native arteries of extremities with rest pain, unspecified extremity”. I25.1 is a non-billable header; I70.229 is billable.

Registry fact

Can these codes be reported together?

Yes, when both are documented.I70.229 lists I25.1 under Excludes2: “arteriosclerotic cardiovascular disease (I25.1-)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code.

Official rule

Is there an Excludes2 relationship?

Yes.I70.229’s tabular entry: “arteriosclerotic cardiovascular disease (I25.1-)”. The note covers I25.1.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

Not comparable.The codes sit in different categories; specificity is only comparable within one category.

Is one a parent or header code?

One is a header.I25.1 is a non-billable header, but I70.229 is not one of its subdivisions.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

I70.229
Atherosclerosis of native arteries of extremities with rest pain, unspecified extremity
↔
I25.1
Atherosclerotic heart disease of native coronary artery

What we found

Yes, when both are documented.I70.229 carries an Excludes2 note covering I25.1: “arteriosclerotic cardiovascular disease (I25.1-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2027

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

Similar descriptions do not make codes interchangeable. The documentation and the official instructions decide which code applies.

Official descriptionDiffers
I25.1

Atherosclerotic heart disease of native coronary artery

I70.229

Atherosclerosis of native arteries of extremities with rest pain, unspecified extremity

StatusDiffers
I25.1
Non-billable header

A header is not reported on a claim; a code beneath it is.

Report instead: I25.10, I25.110, I25.111, I25.112, I25.118

I70.229
Billable
Excludes2Differs
I25.1
  • atheroembolism (I75.-)
  • atherosclerosis of coronary artery bypass graft(s) and transplanted heart (I25.7-)
  • non-ischemic myocardial injury (I5A)
I70.229
  • atherosclerosis of bypass graft of extremities (I70.30-I70.79)
  • arteriosclerotic cardiovascular disease (I25.1-)
  • arteriosclerotic heart disease (I25.1-)
  • atheroembolism (I75.-)
  • cerebral atherosclerosis (I67.2)
  • coronary atherosclerosis (I25.1-)
  • mesenteric atherosclerosis (K55.1)
  • precerebral atherosclerosis (I67.2)
  • primary pulmonary atherosclerosis (I27.0)
Use additional codeDiffers
I25.1
  • code, if applicable, to identify:
  • coronary atherosclerosis due to calcified coronary lesion (I25.84)
  • coronary atherosclerosis due to lipid rich plaque (I25.83)
I70.229
  • code, if applicable, to identify chronic total occlusion of artery of extremity (I70.92)
  • code to identify:
  • exposure to environmental tobacco smoke (Z77.22)
Code alsoDiffers
I25.1
  • the presence of hypertension (I10-I1A)
I70.229

None at this code

CategoryDiffers
I25.1

I25 Chronic ischemic heart disease

I70.229

I70 Atherosclerosis

ChapterSame for both

I00-I99 — Diseases of the Circulatory System (I00-I99)

IncludesDiffers
I25.1
  • Atherosclerotic cardiovascular disease
  • Coronary (artery) atheroma
  • Coronary (artery) atherosclerosis
  • Coronary (artery) disease
I70.229
  • any condition classifiable to I70.21-
  • chronic limb-threatening ischemia NOS of native arteries of extremities
  • chronic limb-threatening ischemia of native arteries of extremities with rest pain
  • critical limb ischemia NOS of native arteries of extremities

No Excludes1, Code first and 7th character note at either code.

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on. In a row that differs, notes every code shares are dimmed.

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Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources