R22 vs R59
R22 (Localized swelling, mass and lump of skin and subcutaneous tissue) compared with R59 (Enlarged lymph nodes), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. R22 carries an Excludes1 note covering R59: “enlarged lymph nodes (R59.-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| R22Localized swelling, mass and lump of skin and subcutaneous tissue | R59Enlarged lymph nodes | |
|---|---|---|
| Billing status | Non-billable header | Non-billable header |
| Classification | R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99) | R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99) |
| Definition | Localized swelling, mass and lump of skin and subcutaneous tissue is a non-billable ICD-10-CM category code (R22). | Enlarged lymph nodes is a non-billable ICD-10-CM category code (R59). |
| Includes | subcutaneous nodules (localized)(superficial) | swollen glands |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources