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R57 vs T88.6

R57 (Shock, not elsewhere classified) compared with T88.6 (Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. R57 carries an Excludes1 note covering T88.6: “anaphylactic shock due to adverse effect of correct drug or medicament properly administered (T88.6)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

R57Shock, not elsewhere classifiedT88.6Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered
Billing statusNon-billable header

Report instead: R57.0, R57.1, R57.8, R57.9

Non-billable header

Report instead: T88.6XXA, T88.6XXD, T88.6XXS

ClassificationR00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionShock, not elsewhere classified is a non-billable ICD-10-CM category code (R57).Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered is a non-billable ICD-10-CM category code (T88.6).
7th characterThe appropriate 7th character is to be added to each code from category T88
Includes
Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
Anaphylactoid reaction NOS
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources