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R80 vs R87.622

R80 (Proteinuria) compared with R87.622 (Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)), from the official CMS tabular data.

Summary

These codes can be reported together when both conditions are documented, because R87.622 lists R80 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

The conditions named and billing status.R80 is “Proteinuria”; R87.622 is “Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)”. R80 is a non-billable header; R87.622 is billable.

Registry fact

Can these codes be reported together?

Yes, when both are documented.R87.622 lists R80 under Excludes2: “abnormal findings on examination of urine, without diagnosis (R80-R82)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code. R80 carries 5 Excludes1 notes and R87.622 carries 10 Excludes1 notes covering other codes; the side-by-side table quotes them.

Official rule

Is there an Excludes2 relationship?

Yes.R87.622’s tabular entry: “abnormal findings on examination of urine, without diagnosis (R80-R82)”. The note covers R80.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

Not comparable.The codes sit in different categories; specificity is only comparable within one category.

Is one a parent or header code?

One is a header.R80 is a non-billable header, but R87.622 is not one of its subdivisions.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

R87.622
Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
↔
R80
Proteinuria

What we found

Yes, when both are documented.R87.622 carries an Excludes2 note covering R80: “abnormal findings on examination of urine, without diagnosis (R80-R82)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2026

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

R80ProteinuriaR87.622Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
Billing statusNon-billable header

Report instead: R80.0, R80.1, R80.2, R80.3, R80.8

Billable
ClassificationR00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)R00-R99 — Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99)
DefinitionProteinuria is a non-billable ICD-10-CM category code (R80).Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL) is a billable ICD-10-CM diagnosis code (R87.622).
Includes—
abnormal findings in secretion and smears from cervix uteri
abnormal findings in secretion and smears from vagina
abnormal findings in secretion and smears from vulva
Excludes1
gestational proteinuria (O12.1-)
abnormal findings on antenatal screening of mother (O28.-)
diagnostic abnormal findings classified elsewhere - see Alphabetical Index
specific findings indicating disorder of amino-acid metabolism (E70-E72)
specific findings indicating disorder of carbohydrate metabolism (E73-E74)
abnormal cytological findings in specimens from cervix uteri (R87.61-)
abnormal cytological findings in specimens from other female genital organs (R87.69)
carcinoma in situ of vagina (histologically confirmed) (D07.2)
vaginal intraepithelial neoplasia I [VAIN I] (N89.0)
vaginal intraepithelial neoplasia II [VAIN II] (N89.1)
vaginal intraepithelial neoplasia III [VAIN III] (D07.2)
dysplasia (mild) (moderate) of vagina (histologically confirmed) (N89.-)
severe dysplasia of vagina (histologically confirmed) (D07.2)
abnormal findings on antenatal screening of mother (O28.-)
diagnostic abnormal findings classified elsewhere - see Alphabetical Index
Excludes2—
vaginal high risk human papillomavirus (HPV) DNA test positive (R87.811)
vaginal low risk human papillomavirus (HPV) DNA test positive (R87.821)
abnormal findings on examination of blood, without diagnosis (R70-R79)
abnormal findings on examination of urine, without diagnosis (R80-R82)
abnormal tumor markers (R97.-)
Use additional code—
code to identify acquired absence of uterus and cervix, if applicable (Z90.71-)

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on.

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Derived from the official CMS ICD-10-CM tabular data (FY2027). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources