R80 ICD-10-CM Code: Proteinuria
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coding at a Glance
- Tabular directives
- 5 Excludes1
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for R80 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on R80 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- gestational proteinuria (O12.1-) Compare R80 vs O12.1 →
- abnormal findings on antenatal screening of mother (O28.-) inherited from R80-R82Compare R80 vs O28 →
- diagnostic abnormal findings classified elsewhere - see Alphabetical Index inherited from R80-R82
- specific findings indicating disorder of amino-acid metabolism (E70-E72) inherited from R80-R82Compare R80 vs E70 →
- specific findings indicating disorder of carbohydrate metabolism (E73-E74) inherited from R80-R82Compare R80 vs E73 →
Coder workflow for R80
MedCoder structured workflow — derived from this code’s own official record
Before you code R80
- R80 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewR80.0, R80.1, R80.2, R80.3, R80.8, R80.9
See the relationships section · Guide: How to choose an ICD-10-CM code →
- Check whether an established diagnosis that explains this sign or symptom is documented. If one is, review whether the documented diagnosis changes the coding pathway: a symptom that is integral to a confirmed diagnosis is not reported separately, while one not routinely associated with it may be. Signs and symptoms are reported when no definitive diagnosis is established (Guidelines I.B.4, I.B.5, I.B.6, I.C.18.b).
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with R80. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support one of the more specific codes beneath R80?
Yes → Select that code and continue the checks below on its own page.
No → R80 cannot be reported as written; query for the specificity its subcategory needs. - Is an established diagnosis that explains this sign or symptom documented?
Yes → Review whether the documented diagnosis changes the coding pathway: a symptom integral to it is not reported separately.
No → Continue — the sign or symptom code stands when no definitive diagnosis is established. - Does the documentation support a condition named in R80’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Consider R80. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Official instructions as workflow
Excludes1 — check before selecting R80(5 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with R80: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
See the official tabular notes · Guidelines I.A.12.a
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: The sign or symptom is documented, and the same record establishes a diagnosis that routinely includes it.
Coding question: Is R80 reported in addition to the diagnosis?
Path: Review the documented diagnosis and whether the classification treats this finding as integral to it.
Reason: Signs and symptoms integral to a confirmed diagnosis are not coded separately; those not routinely associated with it may be reported when present (Guidelines I.B.5, I.B.6, I.C.18.b).
Documentation: Both the condition R80 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name R80 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 9 Excludes2 notes across 2 chapters: N39 — Other disorders of urinary system, R83 — Abnormal findings in cerebrospinal fluid, R83-R89 — Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89), R84 — Abnormal findings in specimens from respiratory organs and thorax, R85 — Abnormal findings in specimens from digestive organs and abdominal cavity, R86 — Abnormal findings in specimens from male genital organs, R87 — Abnormal findings in specimens from female genital organs, R88 — Abnormal findings in other body fluids and substances, R89 — Abnormal findings in specimens from other organs, systems and tissues.
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
Contextual Map
Every relationship of R80 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run R80 with these 15 related codes in Claim Check
Hierarchy
- R00-R99 — Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified (R00-R99) (R00-R99)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- R80-R82 — Abnormal findings on examination of urine, without diagnosis[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Excludes1
- E70 — Disorders of aromatic amino-acid metabolism[Excludes1]: “specific findings indicating disorder of amino-acid metabolism (E70-E72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E71 — Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism[Excludes1]: “specific findings indicating disorder of amino-acid metabolism (E70-E72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E72 — Other disorders of amino-acid metabolism[Excludes1]: “specific findings indicating disorder of amino-acid metabolism (E70-E72)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E73 — Lactose intolerance[Excludes1]: “specific findings indicating disorder of carbohydrate metabolism (E73-E74)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- E74 — Other disorders of carbohydrate metabolism[Excludes1]: “specific findings indicating disorder of carbohydrate metabolism (E73-E74)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- O12.1 — Gestational proteinuria[Excludes1]: “gestational proteinuria (O12.1-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- O28 — Abnormal findings on antenatal screening of mother[Excludes1]: “abnormal findings on antenatal screening of mother (O28.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes (9)
- N39 — Other disorders of urinary system[Excludes2]: “proteinuria NOS (R80.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R83 — Abnormal findings in cerebrospinal fluid[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R83-R89 — Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R84 — Abnormal findings in specimens from respiratory organs and thorax[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R85 — Abnormal findings in specimens from digestive organs and abdominal cavity[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R86 — Abnormal findings in specimens from male genital organs[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R87 — Abnormal findings in specimens from female genital organs[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R88 — Abnormal findings in other body fluids and substances[Excludes2]: “abnormal findings on examination of urine, without diagnosis (R80-R82)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 1 more
Nearest codes
- R80.0 — Isolated proteinuria[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- R80.1 — Persistent proteinuria, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- R80.2 — Orthostatic proteinuria, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- R80.3 — Bence Jones proteinuria[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- R80.8 — Other proteinuria[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- R80.9 — Proteinuria, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can R80 be billed directly?
No. R80 (Proteinuria) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "R80 — Proteinuria." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/r80-proteinuria
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionProteinuria
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to R80 in its code family, with their registry titles.