O12.1 ICD-10-CM Code: Gestational proteinuria
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coder workflow for O12.1
MedCoder structured workflow — derived from this code’s own official record
Before you code O12.1
- O12.1 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewO12.10, O12.11, O12.12, O12.13, O12.14, O12.15
See the relationships section · Guide: How to choose an ICD-10-CM code →
- Confirm the condition is documented as complicating the pregnancy, childbirth, or the puerperium, and check the trimester where the code carries one and the fetus character where the category requires it. Chapter 15 codes belong on the maternal record only and take sequencing priority over codes from other chapters. It is the provider’s responsibility to state that a condition is not affecting the pregnancy; the trimester is assigned from the documentation (Guidelines I.C.15.a, I.C.15.a.1, I.C.15.a.3).
Choose the right path
- Does the documentation support one of the more specific codes beneath O12.1?
Yes → Select that code and continue the checks below on its own page.
No → O12.1 cannot be reported as written; query for the specificity its subcategory needs.
Consider O12.1. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- Trimester
- Assigned from the documented trimester at the encounter, or the trimester in which the condition developed for inpatient stays (Guidelines I.C.15.a.3).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name O12.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 1 Excludes1 note: R80 — Proteinuria.
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 1 Excludes2 note: O99.4 — Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium (via O12.-).
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
Related Codes
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Proteinuria”; these codes share that main term but sit in a different category of the Tabular List.
N06.0 — Isolated proteinuria with minor glomerular abnormality (isolated, with glomerular lesion, minimal change), N06.1 — Isolated proteinuria with focal and segmental glomerular lesions (isolated, with glomerular lesion, focal and segmental hyalinosis or sclerosis), N06.20 — Isolated proteinuria with diffuse membranous glomerulonephritis, unspecified (isolated, with glomerular lesion, membranous), N06.29 — Other isolated proteinuria with diffuse membranous glomerulonephritis (isolated, with glomerular lesion, membranous, with diffuse membranous glomerulonephritis), N06.3 — Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis (isolated, with glomerular lesion, mesangial proliferative), N06.4 — Isolated proteinuria with diffuse endocapillary proliferative glomerulonephritis (isolated, with glomerular lesion, diffuse, endocapillary proliferative glomerulonephritis), N06.5 — Isolated proteinuria with diffuse mesangiocapillary glomerulonephritis (isolated, with glomerular lesion, diffuse, mesangiocapillary glomerulonephritis), N06.6 — Isolated proteinuria with dense deposit disease (isolated, with glomerular lesion, dense deposit disease), N06.7 — Isolated proteinuria with diffuse crescentic glomerulonephritis (isolated, with glomerular lesion, diffuse, crescentic glomerulonephritis), N06.8 — Isolated proteinuria with other morphologic lesion (isolated, with glomerular lesion, specified pathology NEC), N06.9 — Isolated proteinuria with unspecified morphologic lesion (isolated, with glomerular lesion), N06.A — Isolated proteinuria with C3 glomerulonephritis (isolated, with glomerular lesion, C3, glomerulopathy), R80.0 — Isolated proteinuria (isolated), R80.1 — Persistent proteinuria, unspecified (persistent), R80.2 — Orthostatic proteinuria, unspecified (postural), R80.3 — Bence Jones proteinuria (Bence Jones), R80.8 — Other proteinuria (specified type NEC), R80.9 — Proteinuria, unspecified
Contextual Map
Every relationship of O12.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run O12.1 with these 2 related codes in Claim Check
Hierarchy
- O00-O9A — Chapter 15: Pregnancy, Childbirth and the Puerperium (O00-O9A) (O00-O9A)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O10-O16 — Edema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes
- R80 — Proteinuria[Excludes1]: “gestational proteinuria (O12.1-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes
- O99.4 — Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium[Excludes2](via O12.-): “hypertensive disorders (O10-O16)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Nearest codes (21)
- O12 — Gestational [pregnancy-induced] edema and proteinuria without hypertension[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.0 — Gestational edema[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.00 — Gestational edema, unspecified trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.01 — Gestational edema, first trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.02 — Gestational edema, second trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.03 — Gestational edema, third trimester[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.04 — Gestational edema, complicating childbirth[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- O12.05 — Gestational edema, complicating the puerperium[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 13 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can O12.1 be billed directly?
No. O12.1 (Gestational proteinuria) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "O12.1 — Gestational proteinuria." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/o12.1-gestational-proteinuria
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionGestational proteinuria
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to O12.1 in its code family, with their registry titles.
- O12.01 — Gestational edema, first trimester
- O12.02 — Gestational edema, second trimester
- O12.03 — Gestational edema, third trimester
- O12.04 — Gestational edema, complicating childbirth
- O12.05 — Gestational edema, complicating the puerperium
- O12.10 — Gestational proteinuria, unspecified trimester
- O12.11 — Gestational proteinuria, first trimester
- O12.12 — Gestational proteinuria, second trimester
- O12.13 — Gestational proteinuria, third trimester
- O12.14 — Gestational proteinuria, complicating childbirth