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T78.0 vs T88.6

T78.0 (Anaphylactic reaction due to food) compared with T88.6 (Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

Yes, when both are documented. T78.0 carries an Excludes2 note covering T88.6: “complications of surgical and medical care NEC (T80-T88)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

No — do not report together. T88.6 carries an Excludes1 note covering T78.0: “anaphylactic shock or reaction due to adverse food reaction (T78.0-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

T78.0Anaphylactic reaction due to foodT88.6Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered
Billing statusNon-billable header

Report instead: T78.00XA, T78.00XD, T78.00XS, T78.01XA, T78.01XD

Non-billable header

Report instead: T88.6XXA, T88.6XXD, T88.6XXS

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionAnaphylactic reaction due to food is a non-billable ICD-10-CM category code (T78.0).Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered is a non-billable ICD-10-CM category code (T88.6).
7th characterThe appropriate 7th character is to be added to each code from category T78The appropriate 7th character is to be added to each code from category T88
Includes
Anaphylactic reaction due to adverse food reaction
Anaphylactic shock or reaction due to nonpoisonous foods
Anaphylactoid reaction due to food
Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
Anaphylactoid reaction NOS
Use additional code
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources