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T78.09XS vs T80

T78.09XS (Anaphylactic reaction due to other food products, sequela) compared with T80 (Complications following infusion, transfusion and therapeutic injection), from the official CMS tabular data.

Summary

These codes can be reported together when both conditions are documented, because T78.09XS lists T80 under Excludes2, which marks them as distinct conditions.

Official rule
What is different?

The conditions named and billing status.T78.09XS is “Anaphylactic reaction due to other food products, sequela”; T80 is “Complications following infusion, transfusion and therapeutic injection”. T80 is a non-billable header; T78.09XS is billable.

Registry fact

Can these codes be reported together?

Yes, when both are documented.T78.09XS lists T80 under Excludes2: “complications of surgical and medical care NEC (T80-T88)”. Excludes2 marks distinct conditions that may both be reported when both are documented.

Official ruleGuide: Excludes1 vs Excludes2

Is there an Excludes1 relationship?

None.Neither entry carries an Excludes1 note that names the other code.

Official rule

Is there an Excludes2 relationship?

Yes.T78.09XS’s tabular entry: “complications of surgical and medical care NEC (T80-T88)”. The note covers T80.

Official ruleGuide: Excludes1 vs Excludes2

Is one more specific?

Not comparable.The codes sit in different categories; specificity is only comparable within one category.

Is one a parent or header code?

One is a header.T80 is a non-billable header, but T78.09XS is not one of its subdivisions.

Registry fact

Are there sequencing instructions?

None.Neither entry carries a Code First or Use Additional Code note that names the other.

Official rule

Are there other coding relationships?

None found.No laterality, encounter-phase, Table of Neoplasms, Table of Drugs and Chemicals, or history-versus-active-disease relationship links these codes.

MedCoder-derived

Official rule: a tabular instructional note or a section of the ICD-10-CM Official Guidelines, quoted as published. Registry fact: the codes’ own published attributes (titles, billable status, position in the hierarchy, code set). MedCoder-derived: a reading MedCoder computes from those facts; it is not itself a rule. How to read the labels

Can these codes be reported together?

Informational

Excludes2 relationship

T78.09XS
Anaphylactic reaction due to other food products, sequela
↔
T80
Complications following infusion, transfusion and therapeutic injection

What we found

Yes, when both are documented.T78.09XS carries an Excludes2 note covering T80: “complications of surgical and medical care NEC (T80-T88)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

What to review

Report both only when the documentation supports both conditions; otherwise report the one documented.

Guide: Excludes1 vs Excludes2Check these on a claim

Why it matters

An Excludes2 note means the excluded condition is not part of the code above it, but a patient can have both. Report both when both are documented.

Source / rule

CMS ICD-10-CM tabular instructional notes

Official guidance behind these answers

  • Section I.A.12.b — Excludes2 · applies to: Excludes2

    A type 2 Excludes note represents “Not included here.” An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

    ICD-10-CM Official Guidelines FY2026

Quoted from the ICD-10-CM Official Guidelines for Coding and Reporting in effect for the release shown. The tabular notes above are the code-level instruction; these sections are the convention that says how such a note is applied. Source document (CMS PDF) · Release and checksum

Side by side

T78.09XSAnaphylactic reaction due to other food products, sequelaT80Complications following infusion, transfusion and therapeutic injection
Billing statusBillableNon-billable header

Report instead: T80.0XXA, T80.0XXD, T80.0XXS, T80.1XXA, T80.1XXD

ClassificationS00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88)
DefinitionAnaphylactic reaction due to other food products, sequela is a billable ICD-10-CM diagnosis code (T78.09XS).Complications following infusion, transfusion and therapeutic injection is a non-billable ICD-10-CM category code (T80).
7th characterThe appropriate 7th character is to be added to each code from category T78The appropriate 7th character is to be added to each code from category T80
Includes—
complications following perfusion
Excludes2
complications of surgical and medical care NEC (T80-T88)
bone marrow transplant rejection (T86.01)
febrile nonhemolytic transfusion reaction (R50.84)
fluid overload due to transfusion (E87.71)
posttransfusion purpura (D69.51)
transfusion associated circulatory overload (TACO) (E87.71)
transfusion (red blood cell) associated hemochromatosis (E83.111)
transfusion related acute lung injury (TRALI) (J95.84)
any encounters with medical care for postprocedural conditions in which no complications are present, such as:
artificial opening status (Z93.-)
closure of external stoma (Z43.-)
fitting and adjustment of external prosthetic device (Z44.-)
burns and corrosions from local applications and irradiation (T20-T32)
complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
mechanical complication of respirator [ventilator] (J95.850)
poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
postprocedural fever (R50.82)
specified complications classified elsewhere, such as:
cerebrospinal fluid leak from spinal puncture (G97.0)
colostomy malfunction (K94.0-)
disorders of fluid and electrolyte imbalance (E86-E87)
functional disturbances following cardiac surgery (I97.0-I97.1)
intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
ostomy complications (J95.0-, K94.-, N99.5-)
postgastric surgery syndromes (K91.1)
postlaminectomy syndrome NEC (M96.1)
postmastectomy lymphedema syndrome (I97.2)
postsurgical blind-loop syndrome (K91.2)
ventilator associated pneumonia (J95.851)
Use additional code—
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)
Code also
, if applicable, place of occurrence, such as:
highway rest stop (Y92.523)
school (private) (public) (state) as the place of occurrence of the external cause (Y92.21-)
service areas as the place of occurrence of the external cause (Y92.52-)
single-family non-institutional (private) house as the place of occurrence of the external cause (Y92.01-)
transport vehicle as the place of occurrence of the external cause (Y92.81-)
—

Notes are the code’s own tabular entry, quoted as published. A note that names the other code is the one the verdict above rests on.

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Derived from the official CMS ICD-10-CM tabular data (FY2026). A coding-rule comparison, not billing advice: payer-specific edits and medical-necessity policy are outside its scope. All data sources