T80.3 vs T80.59XS
T80.3 (ABO incompatibility reaction due to transfusion of blood or blood products) compared with T80.59XS (Anaphylactic reaction due to other serum, sequela), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. T80.59XS carries an Excludes1 note covering T80.3: “ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| T80.3ABO incompatibility reaction due to transfusion of blood or blood products | T80.59XSAnaphylactic reaction due to other serum, sequela | |
|---|---|---|
| Billing status | Non-billable header Report instead: T80.30XA, T80.30XD, T80.30XS, T80.310A, T80.310D | Billable |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | ABO incompatibility reaction due to transfusion of blood or blood products is a non-billable ICD-10-CM category code (T80.3). | Anaphylactic reaction due to other serum, sequela is a billable ICD-10-CM diagnosis code (T80.59S). |
| 7th character | The appropriate 7th character is to be added to each code from category T80 | The appropriate 7th character is to be added to each code from category T80 |
| Includes | complications following perfusion | complications following perfusion |
| Use additional code | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources