T80.5 vs T88.1
T80.5 (Anaphylactic reaction due to serum) compared with T88.1 (Other complications following immunization, not elsewhere classified), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. T88.1 carries an Excludes2 note covering T80.5: “anaphylactic shock due to serum (T80.5-)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Yes, when both are documented. T88.1 carries an Excludes2 note covering T80.5: “complication following infusion, transfusion and therapeutic injection (T80.-)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| T80.5Anaphylactic reaction due to serum | T88.1Other complications following immunization, not elsewhere classified | |
|---|---|---|
| Billing status | Non-billable header Report instead: T80.51XA, T80.51XD, T80.51XS, T80.52XA, T80.52XD | Non-billable header |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Anaphylactic reaction due to serum is a non-billable ICD-10-CM category code (T80.5). | Other complications following immunization, not elsewhere classified is a non-billable ICD-10-CM category code (T88.1). |
| 7th character | The appropriate 7th character is to be added to each code from category T80 | The appropriate 7th character is to be added to each code from category T88 |
| Includes | complications following perfusion Allergic shock due to serum Anaphylactic shock due to serum Anaphylactoid reaction due to serum | Generalized vaccinia Rash following immunization |
| Use additional code | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources