T80.51XD vs T80.6
T80.51XD (Anaphylactic reaction due to administration of blood and blood products, subsequent encounter) compared with T80.6 (Other serum reactions), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. T80.51XD carries an Excludes1 note covering T80.6: “other serum reaction (T80.6-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| T80.51XDAnaphylactic reaction due to administration of blood and blood products, subsequent encounter | T80.6Other serum reactions | |
|---|---|---|
| Billing status | Billable | Non-billable header Report instead: T80.61XA, T80.61XD, T80.61XS, T80.62XA, T80.62XD |
| Classification | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) | S00-T88 — Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) |
| Definition | Anaphylactic reaction due to administration of blood and blood products, subsequent encounter is a billable ICD-10-CM diagnosis code (T80.51D). | Other serum reactions is a non-billable ICD-10-CM category code (T80.6). |
| 7th character | The appropriate 7th character is to be added to each code from category T80 | The appropriate 7th character is to be added to each code from category T80 |
| Includes | complications following perfusion | complications following perfusion Intoxication by serum Protein sickness Serum rash |
| Use additional code | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) | code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) code(s) to identify the specified condition resulting from the complication code to identify devices involved and details of circumstances (Y62-Y82) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources